drugstr
Central, NJ
Male, 61
I have worked as a drug discovery scientist for over 30 years performing experiments to help identify novel chemical compounds for their potential in treating diseases in the areas of infection, inflammation and cardiovascular disorders. I have a good familiarity with the entire process from discovery to safety to clinical trials and even marketing. Ask me about the business of Big Pharma. I’m happy to comment on any and all hot-button issues. My opinions are quite often not pro-business.
This is really not in my wheel house, but I’ll tell you what I think I know. Clinical researchers in big pharma are typically MDs. They interface between scientific groups in house and outside physicians who run the trials. They have a non-MD support staff which is more or less a dead end. One simply can’t advance without an MD. This sort of work does not fit with your business training. Surely, clinical research has a management arm, but I’m sorry, I can’t tell you how to get there. Increasingly, big pharma tends to outsource a lot of their clinical work to CROs (contract research organizations). Search for them. Breaking in to the business end of one of these might be easier since they are smaller, growing and adapting. Down the road you might be able to network to something bigger and better. Hope this helps.
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Initial patent applications are filed early in the discovery process. As soon as a novel chemical structure is identified as having pharmacological properties a very lengthy, general application is authored that claims therapeutic benefits for every conceivably related medical condition and includes every imaginable chemical modification to that structure. During the development process additional patents might be filed for hitherto unexpected uses and for novel formulation and manufacturing processes.
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Sorry for the late response. I have no expertise in this area. I hope by now you have resolved your issue. Best of luck.
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I can't answer because I pay no attention to him.
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Ask the person about the last presentation that he or she made and to send you a copy of the slide deck. If you receive it, look it over and ask questions about it. You'll be able to tell from the answers whether he/she is legit.
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Trump spoke without thinking - disinfectants are poisons. Hydroxychloroquine was a silly attempt at being a hero. A swing and a miss, not a home run. Your question is vague. Are you asking about killing the virus in the air or on surfaces, or how to best avoid infection, or what's the best treatment for the disease? Answers to the first two are described in the media daily, as for the last my opinion is oxygen, anti-inflammatories and an appropriate anti-viral (not yet invented).
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I have the same questions. The answers are not very clear. The FDA has approved its use for certain rare seizure disorders and is useful in reducing nausea and vomiting in cancer chemotherapy patients. Other common claims, not formerly established indications, are chronic pain, inflammation, anxiety, appetite and several mental health conditions. Best usage - replace opiates for chronic pain. Judging effectiveness clinically has got to be difficult since therapeutic success is subjective. I imagine it's hard to identify a patient's true need versus desire for it. As far as safety goes, there are the dangers associated with intoxication and smoking probably carries risks similar to tobacco.
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